Growth factor therapy and autologous lymph node transfer in lymphedema.
Identifieur interne : 005877 ( Main/Exploration ); précédent : 005876; suivant : 005878Growth factor therapy and autologous lymph node transfer in lymphedema.
Auteurs : Pauliina Hartiala [Finlande] ; Anne M. SaaristoSource :
- Trends in cardiovascular medicine [ 1873-2615 ] ; 2010.
Descripteurs français
- KwdFr :
- Animaux, Association thérapeutique, Humains, Lymphangiogenèse (), Lymphangiogenèse (physiologie), Lymphoedème (), Lymphoedème (traitement médicamenteux), Modèles animaux de maladie humaine, Noeuds lymphatiques (transplantation), Protéines et peptides de signalisation intercellulaire (usage thérapeutique), Système lymphatique (physiopathologie), Transplantation autologue.
- MESH :
- physiologie : Lymphangiogenèse.
- physiopathologie : Système lymphatique.
- traitement médicamenteux : Lymphoedème.
- usage thérapeutique : Noeuds lymphatiques, Protéines et peptides de signalisation intercellulaire.
- Animaux, Association thérapeutique, Humains, Lymphangiogenèse, Lymphoedème, Modèles animaux de maladie humaine, Transplantation autologue.
English descriptors
- KwdEn :
- Animals, Combined Modality Therapy, Disease Models, Animal, Humans, Intercellular Signaling Peptides and Proteins (therapeutic use), Lymph Nodes (transplantation), Lymphangiogenesis (drug effects), Lymphangiogenesis (physiology), Lymphatic System (physiopathology), Lymphedema (drug therapy), Lymphedema (surgery), Transplantation, Autologous.
- MESH :
- chemical , therapeutic use : Intercellular Signaling Peptides and Proteins.
- drug effects : Lymphangiogenesis.
- drug therapy : Lymphedema.
- physiology : Lymphangiogenesis.
- physiopathology : Lymphatic System.
- surgery : Lymphedema.
- transplantation : Lymph Nodes.
- Animals, Combined Modality Therapy, Disease Models, Animal, Humans, Transplantation, Autologous.
Abstract
Lymphedema after cancer treatment is a common clinical challenge, but curative treatment options are rarely available. Lymph node transfer is a novel technique in lymphedema surgery. Lymphatic tissue can be transferred as a vascularized free flap, but in this technique the lymphatic vascular network is expected to regrow spontaneously. Recently, we have learned how to regulate the growth of lymphatic vessels in experimental models. We envision that lymph node transfer should be combined with lymphatic growth factor therapy in the treatment of lymphedema patients.
DOI: 10.1016/j.tcm.2011.11.008
PubMed: 22433650
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Lymphedema after cancer treatment is a common clinical challenge, but curative treatment options are rarely available. Lymph node transfer is a novel technique in lymphedema surgery. Lymphatic tissue can be transferred as a vascularized free flap, but in this technique the lymphatic vascular network is expected to regrow spontaneously. Recently, we have learned how to regulate the growth of lymphatic vessels in experimental models. We envision that lymph node transfer should be combined with lymphatic growth factor therapy in the treatment of lymphedema patients.</div>
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